Generally, epithelial cells must organize in three dimensions to form functional tissue sheets.Here we investigate one such sheet, the Drosophila embryonic epidermis, and the morphogenetic NUTRA SEA LIQUID GELS processes organizing cells within it.We report that epidermal morphogenesis requires the proper distribution of the apical polarity determinant aPKC.Specifically, we find roles for the kinases GSK3 and aPKC in cellular alignment, asymmetric protein distribution, and Bike Parts - Tires - 27" adhesion during the development of this polarized tissue.
Finally, we propose a model explaining how regulation of aPKC protein levels can reorganize both adhesion and the cytoskeleton.